Article Analysis of Self Management Interventions for...

There are a number of key factors about the article by Evellen Heirich et al, Self-management interventions for type 2 diabetes: a systematic review that lend themselves to potential use in clinical practice. This article was at variance with a significant amount of research articles in that there was no original research performed within this study. Instead, the data collection methodology simply consisted of analyzing previously existent research for different practices used to ameliorate patients afflicted with type 2 diabetes. In that sense this article functions as a prolonged literary review. There were both positive and negative aspects of this type of approach to research, the latter of which includes the relatively small sample size only 19 articles were analyzed and the fact that the wide variety of the types of research performed in the articles made it increasingly difficult to come to a consensus about certain measures. The authors of this journal article initiated research into this subject by entering certain key words related to self-management techniques and practices for type 2 diabetes in three major journal research engines. What is notable about this process is that the literature review that accompanies most research documents actually doubled as the actual research performed itself, since the authors merely analyzed the studies and findings of the journal articles they deemed relevant to their review of existing literature. The initial titles thatShow MoreRelatedThe Management Of Diabetes During Primary Care1704 Words   |  7 Pages The Management of Diabetes in Primary Care: How to Improve HbA1c levels Ellen C. 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Article one, â€Å"The effect of Educational Interventions on Glycemic Control in Patients with Type 2 Diabetes Mellitus†Read MoreA Brief Note On Diabetes And Its Effects On The Lives Of People Suffering From Diabetes Essay2303 Words   |  10 PagesIntroduction Diabetes is a chronic illness that effects a large number of the population, 243,125 New Zealanders were diagnosed according to the 2013 census (Diabetes New Zealand, 2014a). Diabetes mellitus is a metabolic disease that causes unstable hyperglycaemia resulting from a defect in insulin secretion or action within the body (Belonwu, Obimba, Ozougwu Unakalamba, 2013). 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Almost all patients that develop diabetes type 2 have prediabetes, a condition where bloodRead MoreDiabetes Mellitus : A Debilitating And Chronic Disease2358 Words   |  10 Pages Diabetes Mellitus is a debilitating and chronic disease in which life long care and rehabilitation is required. According to the World Health Organization, diabetes affects over 300 million people worldwide, and continues to rise each year. There are three main categories of diabetes; type 1, type 2 and gestational diabetes. The pathophysiology of diabetes mellitus is related to insulin, which is a hormone secreted by the cells of the pancreas. (WHO) Insulin is responsible for maintaining an idealRead MoreUse Of The Telephone For Diabetes Education Affects Glycemic Control ( Hba1c ) And Weight Management3156 Words   |  13 PagesEducation in the Management of Diabetes Mellitus Lajuana D. Campbell University of Central Florida NGR 6801 – Spring 2015 Abstract In 2012 it was estimated that 1.5 million deaths worldwide were caused by diabetes mellitus. Diabetes mellitus requires self-managing by the patients. However, many patients have difficulty managing to achieve appropriate glycemic control. With a significant issue being lack of knowledge and access to healthcare of those diagnosed with diabetes, other methodsRead MoreUse Of The Telephone For Diabetes3156 Words   |  13 PagesEducation in the Management of Diabetes Mellitus Lajuana D. Campbell University of Central Florida NGR 6801 – Spring 2015 Abstract In 2012 it was estimated that 1.5 million deaths worldwide were caused by diabetes mellitus. Diabetes mellitus requires self-managing by the patients. However, many patients have difficulty managing to achieve appropriate glycemic control. With a significant issue being lack of knowledge and access to healthcare of those diagnosed with diabetes, other methods

Historical Background of the 1987 Constitution - 3415 Words

THE BACKGROUND OF THE PRESENT CONSTITUTION Historical Background of the 1987 Constitution The history of the 1987 Constitution began on 11 April 1899, the date when the Treaty of Paris between the United and Spain of 10 December 1898 became effective upon the exchange of instruments of ratification of both countries. But the sources of the 1987 Constitution are (i) McKinley s Instructions to the Second Philippine Commission; (ii) Spooner Amendment; (iii) Philippine Bill of 1902; (iv) Jones Law of 1916, otherwise known as the Philippine Autonomy Act; (v) 1935 Constitution; (vi) 1973 Constitution and (vi) Freedom Constitution of 1986 and its implementing orders. Treaty of Paris Under the Treaty of Paris, the Philippines was†¦show more content†¦The Bill also defined for the first time who the citizens of the Philippines were. They were all the inhabitants of the Philippine islands who were subjects of Spain as of 11 April 1899, who continued to reside therein, and all the children born subsequent thereto. This definition is still good law today. Jones Law On 29 August 1916, the US Congress passed the Jones Law, otherwise known as the Philippine Autonomy Act. It established a tripartite government with real separation of powers; this was the prototype of our present set-up. The executive power was in the hands of an American Governor-General, who was independent of the Legislature, and who was given the power to suspend the writ of habeas corpus and impose martial law without the recommendation of the Legislature. The Legislature was composed of the Senate and the House of Representatives, all composed of Filipinos. The judiciary continued to be made up of the Supreme Court, the CFIs and Justice of Peace Courts. 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Knowledge Management KM Council Samples †MyAssignmenthelp.com

Question: Discuss about the Knowledge Management KM Council. Answer: Introduction According to Saini (2012), knowledge plays a significant role in making organizations to meet their goals. Although some companies may wish to take various decisions which impact employees, retaining knowledge remains critical in all decisions. Downsizing without considering knowledge can make an organization to experience different challenges which may lead to its closure. Utilizing the right strategies while downsizing is fundamental. After realizing the company was experiencing challenges especially after the end of cold war, northern gate (NG) senior management took the decision of downsizing while retaining knowledge and expertise. The company understood that Knowledge management (KM) and expertise would play a significant role in preventing massive brain drain (McFarlane, 2012). The company under the leadership of smith utilized various strategies including coming up with KM council and conducting knowledge audit to ensure the goal of downsizing while maintaining knowledge and expertise was attained. Case Study Analysis and KM Objectives Identification and Justification Initially, the company did not analyse the employees to know whether they were sharing knowledge. The management took a creditable move to come up with a strategy of identifying if the employees were sharing knowledge. The decision to analyse if employees where aware about the value of sharing knowledge means the management had started realizing that something was wrong because the company was experiencing difficulties in meeting its goals. The end of cold war would make this company to experience various challenges because most of the products which the company produced were used during that time. Based on this factor, and bearing in mind that some of the employees had started quitting the organization, it meant the company was experiencing various problems which would be threat to the success of the organization. According to Huang (2014), failing to address some issues especially those which impact workforce can make an organization to close down. The great success which smith and his team attained will benefit the company in various ways, including coming up with innovative products. The company has different autonomous business units which include information and services, electronics, aerospace and ships. The fact that the company was trying to down size, maintaining knowledge and expertise was important for this units to remain in operation (Ologbo, 2015). After identifying that the organization was experiencing problems, the senior management to down size while retaining knowledge and expertise. The objective of undertaking this process was to ensure the company remains with few employees but with proper knowledge and skills. The company was aware that with the end of cold war and other factors that would provide it with market opportunities, the large number of employees would have no purpose. The company also wanted to retain knowledge because it wanted to have a team that would effectively contribute in production of products which the company was producing. One of NGs main object for knowledge management was to ensure skills and expertise were well utilized to make the company to continue performing better. Great number of employees who were leaving the organization after would significantly impact its performance, bearing in mind that some of them were those who had technical knowledge in some areas that were critical based of the products that the company was producing. Critical Success Factors The ACSs strategy of downsizing while maintaining knowledge succeeded because smith ensured the right procedures were used. Because it is fundamental for employees to understand that knowledge sharing is critical for good performance of an organization, smith considered surveys to find out if the staff members were aware about the importance of sharing know-how with their colleagues (Goel, 2010). The fact that the largest number of them reported to know the value of knowledge sharing means KM would be effective in this company. The fact that the employees understands the value of sharing knowledge will make them to work as teams and improve quality and quantity (Meharabani, 2012). When employees with good knowledge team up while undertaking task, they share ideas, skills and experiences which in turn makes the company to realize success. Understanding the importance of sharing knowledge with their counterparts will also make the employees to assist the company to come up with innovative products. Georgieff (2013) argues that downsizing without retaining knowledge can make a company to experience challenges which can lead to its closure. The fact that ACS succeeded in retaining knowledge and reducing the number of employees, it will remain in operation and save the money which would be used to pay salaries. According to Petter (2014), critical thinking assists organizations to overcome problems which can impact knowledge management. John smiths idea of requesting ACS to implement appropriate KM initiative was right because it would assist in preventing further loss of knowledge and expertise in the organization. Huang (2014) states that before addressing any problem which impact an organization, it is always advisable to first consider what triggers the problem. Before launching the KM initiative, Smith and his team considered to identify the best strategies to identify the barriers which prevented the staff members from sharing information with their colleagues. Alongside the end of cold war which provided the company with opportunities to sell their products, lack of sharing knowledge among the employees could be one of the factor that was making the company to experience challenges. Having identified that employees were aware that sharing information with their counterparts was important, it would be simple for the management to manage knowledge and expertise. NGs decision to analyse the level of knowledge sharing among the employees was fundamental because it assisted the company to understand whether the employees were aware about the importance of knowledge sharing or not (Malgeri, 2013). It was a surprise after the audit was conducted to realize that the employees were aware about the value of sharing knowledge with their counterparts. This means utilization of proper strategies to retain knowledge would make the company to realize great success. According to Goel (2010), organizations only succeed in knowledge management if employees understand the importance of knowledge in workplace. Appointing KM council which emphasized mostly emphasized on knowledge assisted smith to identify that the employees were aware about the value of sharing knowledge with their counterparts. The step by step analysis and good audit process were also significant contributors to the success of that process. Before thinking of the strategies which can effectively manage knowledge in an organization, it is advisable to first consider the factors which can make the staff members think of leaving the company (Omotayo, 2010). Smith was keen in incorporating this factor in the strategies for knowledge management because he advised the KM council to identify the subject matter. The good leadership of smith, assisted the process of downsizing while maintaining knowledge and expertise to be deemed successful. After conducting the whole process, the management managed to reduce workforce from 8000 to 6000 and adapted KM. this means the company will have the right number of employees based on the tasks available. In addition to that, it will also benefit by having employees who can utilize their skills effectively for the success of the organization Having successfully downsized while maintaining knowledge and expertise, this company will be able to realize less cost when it comes to salaries. It will also realize high quality work and great production. Maintaining knowledge will also make it to be more innovative. Having the right number of employees with good knowledge helps an organization to remain successful. Bibliography Georgieff, M., 2013. Who Owns Knowledge Management within Your Federal Agency?. The Public Manager, 42(3), pp. 65-75. Goel, G. R., 2010. Knowledge Management as a Process to Develop Sustainable Competitive Advantage. South Asian Journal of Management, 17(3), pp. 547-562. Huang, L.-S. C.-P., 2014. Knowledge Management Adoption and Diffusion Using Structural Equation Modeling. Global Journal of Business Research, 8(1), pp. 78-90. Malgeri, J., 2013. Enhancing the Knowledge Management Capabilities of Federal Agencies: Implementation of Effective Knowledge Management Can Improve Performance in Government Agencies. The Public Manager, 39(3), pp. 254-289. McFarlane, D., 2012. Personal Knowledge Management: Individual, Organizational and Social Perspectives. Journal of Applied Management and Entrepreneurship, 17(2), pp. 58-75. Mehrabani, S. M., 2012. Knowledge Management and Innovation Capacity. Journal of Management Research, 4(2), pp. 45-56. Ologbo, A. K., 2015. Knowledge Management Processes and Firm Innovation Capability: A Theoretical Model. Asian Social Science, 11(18), pp. 58-75. Omotayo, F. O., 2015. Knowledge Management as an Important Tool in Organisational Management: A Review of Literature. Library Philosophy and Practice, pp. 124-135. Petter, G., 2014. Knowledge Management Strategy in Professional Service Firms. Advances in Management, 7(3), pp. 12-24. Saini, R., 2012. Impact of Knowledge Management Practices on Selected Industries: A Structural Equation Modeling Approach. Management Marketing, 8(4), pp. 102-112.

Tregs in Allergies and Autoimmune Diseases

Abstract Tregs refer to subpopulations of T cells that play a role in suppressing the autoimmunity of diseases. They maintain self-tolerance and homeostasis of body’s immunity. Tregs inhibit the proliferation of T cells; hence, they play a role in the prevention of the autoimmunity.Advertising We will write a custom essay sample on Tregs in Allergies and Autoimmune Diseases specifically for you for only $16.05 $11/page Learn More In a lipopolysaccharide challenge carried out using mice models, Tregs were found to control CD4+T cells from causing hypersensitivity, which pointed to their indispensable role in the control of autoimmunity diseases. The investigation of the role of Tregs in allergies entailed in vitro experiments in which models of mouse CD4+CD25+ T cells were used. The cells were found to suppress differentiation of Th2 from CD4+ cells, which inhibited IgE. The IgE acts against antigens that cause allergies. Introduction Tregs (regula tory T cells) prevent autoimmune diseases and infections that arise from organ pathogens. The roles of Tregs in autoimmune diseases and allergies have resulted in a lot of interest. As a result, there have been many studies by clinical researchers to ascertain the functions of Tregs in the allergies and autoimmune diseases. For example, Okeke, Okwor and Uzonna (656) conducted a study to investigate the functions of Tregs. The study entailed a lipopolysaccharide (LPS) in which Tregs were found to prevent unregulated immune activation. In relation to the allergies, the studies investigated the effects of subsets of Tregs in influencing IgE population. The following paper investigates Tregs and their roles in the prevention of allergies and autoimmune diseases. Goals of the Study Prevention of autoimmune diseases is one of the key areas of interest in studies related to Tregs. Schmidt, Oberle and Krammer (4) noted that the function of Tregs in the maintenance of peripheral tolerance ca nnot be underestimated. Therefore, the first goal of this study is to determine the function of Tregs in the immune activation. The second goal is to determine the role of Tregs in the regulation of allergic diseases. Techniques In the study to investigate the role of Tregs in the maintenance of peripheral tolerance, knock out models of murine lymphocyte gene were used. The study included the use of non-lethal dose of LPS. Mice that were SCID or RAG 1 deficient and lacked the T and B cells were investigated for the LPS susceptibility (Okeke, Okwor and Uzonna 656).Advertising Looking for essay on health medicine? Let's see if we can help you! Get your first paper with 15% OFF Learn More In the investigation of the role of Tregs in reducing allergic sensitization, studies that included in vitro differentiation of Th2 from CD4+T cells (Robinson, Larchà © Durham 1389). Findings In the investigation of the role of Tregs in the autoimmunity, depletion of the Tregs resulte d in increased sensitivity to LPS. However, the mice that lacked T and B cells were not sensitive to LPS. The depletion of Tregs resulted in increase in CD4 (+) T cells proliferation that responded to the LPS challenge. The CD4 (+) T cells are normally pathologic. The cells exaggerated the activation of the immune system, which negatively affected the survival of LPS (Okeke, Okwor and Uzonna 659). Investigation of functions of Tregs in allergies found that models of mice CD4+CD25+T cells suppressed the differentiation of Th2 from CD4+T cells. The high levels of IgE were reduced by CD4+CD25–T cells. Transgenic mice with monoclonal populations of T cells increased the levels of IgE. In vitro experiments of models of mouse CD4+CD25+T cells suppressed the differentiation of Th2 in vitro from CD4+T cells. The monoclonal populations of T cells increased the levels of IgE. Discussion The subpopulations of T cells prevent infections induced organ pathology. Tregs act by inhibiting th e TCR Induced proliferation. In the LPS challenge, the use of the murine suppressed the T cells proliferation thus Tregs produced TGF–Î ² that controls autoimmunity. According to Okeke, Okwor and Uzonna (661), subsets of Tregs both in mice and in humans play an importance role in the pathogenesis of autoimmune diseases. Tregs control the homeostasis of T cells by suppressing the proliferation of effectors T cells. The result is the increase in self-tolerance. In vivo experiments have showed that the absence of Tregs leads to autoimmune diseases such as gastritis, arthritis, and thyroiditis. IgE is produced in atopic allergic sensitization. The IgE protects the body from environmental antigens. In normal cases, the control of allergies is done by use of allergen injection immunotherapy (Robinson, Larchà © and Durham 1389). The mechanism involves the modulation of Th2 response.Advertising We will write a custom essay sample on Tregs in Allergies and Autoimmune Diseases s pecifically for you for only $16.05 $11/page Learn More According to Palomares (1236), the subsets of Tregs share common features of Foxp3 expression and inhibit the cytokine IL-10 (TGF–Î ²). The inhibition of functional Tregs compromises the body’s response to allergies. The implication is that the Tregs prevent the responses of IgE. Thus, Tregs contribute to the early development of allergies. Conclusion Tregs enhance self-tolerance and maintain homeostasis by suppression of effectors T cells. The inhibition of the proliferation of T cells results in actions that control autoimmunity diseases. On the other hand, the inhibitory properties of Tregs reduce the population of IgE; hence, compromising body’s response to allergies. Therefore, in designing therapies for allergies, the actions of Tregs and their effects on IgE should be considered. Works Cited Okeke, Emeka, Ifeoma Okwor, and Jude Uzonna. â€Å"Regulatory T cells restrain CD4+ T cells from causing unregulated immune activation and hypersensitivity to lipopolysaccharide challenge.† The Journal of Immunology 193.2 (2014): 655- 662. Print. Palomares, Oscar. â€Å"Role of Tregs in immune regulation of allergic diseases.† European Journal of Immunology 40.5 (2010): 1232-1240. Print. Robinson, Douglas, Mark Larchà ©, and Stephen Durham. â€Å"Tregs and allergic disease.† Journal of Clinical Investigation 114.10 (2004): 1389-1391.Print. Schmidt, Angelika, Nina Oberle, and Peter Krammer. â€Å"Molecular mechanisms of Treg- mediated T cell suppression.† Frontiers in Immuneology 3.1 (2012): 2-13. Print. This essay on Tregs in Allergies and Autoimmune Diseases was written and submitted by user Annabella K. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.